Synthesis of Pyrene Containing Building Blocks for Dendrimer Synthesis

Abstract

Efficient syntheses of the novel, pyrene containing branched building blocks 10, 13, 22, 25 and of a pyrene based core molecule 16 for the construction of dendrimers are reported. The main tool is a Suzuki cross-coupling. The functional groups for further growth are amines and carboxylic acids, which were used in an orthogonally protected fashion. It was proven that the building blocks could be assembled to a low generation dendrimer 17.

Key words

arenas - dendrimers - cross-coupling - pyrenes - protecting groups

References

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5

Beinhoff, M.; Weigel, W.; Jurczok, M.; Rettig, W.; Modrakowski, C.; Brüdgam, I.; Hartl, H.; Schlüter, A. D. Eur. J. Org. Chem. submitted.

7

We consider a dummy a non-fluorescent fragment of virtually the same space demand as the fluorescent probe.

14

For example, see: Vetter, S.; Zhang, A.; Koch, S.; Schlüter, A. D. Macromol. Chem. Phys. submitted.