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Synlett 2001; 2001(11): 1739-1742
DOI: 10.1055/s-2001-18096
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Facile Assembly of 2,4-Orthogonally-Functionalized Oxazoles: Useful Bidirectional Linchpins

Amos B. Smith III.* , Kevin P. Minbiole, Scott Freeze
  • *Department of Chemistry, Monell Chemical Senses Center and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, PA 19104, USA; Fax + 1(215)8 98 51 29; E-mail: smithab@sas.upenn.edu
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Publication Date:
29 October 2001 (online)

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Development of a facile synthesis of 2,4-disubstituted oxazoles, useful 2,4-orthogonally-functionalized oxazole linchpins, has been achieved.

heterocycle synthesis - oxazolone cyclization - diazo compounds - oxazoles - orthogonally-functionalized linchpin