Palladium-Catalyzed Cross-Coupling Reaction of Aryltriethoxysilanes with Aryl Bromides under Basic Aqueous Conditions

Abstract

Aryltriethoxysilanes were cross-coupled with aryl bromides in high yield in the presence of a palladium catalyst and aqueous sodium hydroxide.

Key words

siloxane derivatives - cross-coupling - palladium catalyst - aryl bromides - biaryls

References

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6

Generally, aryltrimethoxysilanes could be prepared from the corresponding arylchlorosilanes. The major product using tetramethyl orthosilicate was diaryl(dimethoxy)silane. See also ref [4b] . Unlike methyl derivatives, ethyl siloxane derivatives are directly prepared by reacting aryl Grignard reagents with tetraethyl orthosilicate in acceptable yields. See Experimental Section.