Zr ⁴⁺ -Catalyzed Efficient Synthesis of α-Aminophosphonates [1]

Abstract

Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride at ambient temperature to afford the corresponding α-aminophosphonates in high yields with high selectivity.

Key words

α-aminophosphonates - diethyl phosphite - imines - zirconium reagents

1

IICT Communication No. 10806.

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1

IICT Communication No. 10806.