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Planta Med 2001; 67(9): 873-875
DOI: 10.1055/s-2001-18838
DOI: 10.1055/s-2001-18838
Letter
© Georg Thieme Verlag Stuttgart · New York
Antifungal Principles from Piper fulvescens
Further Information
Publication History
December 12, 2000
February 4, 2001
Publication Date:
06 December 2001 (online)
Abstract
Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans against five fungi strains were determined. Conocarpan showed the widest activity, whereas eupomatenoid 6 was the most active against dermatophytes.