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Endoscopy 2002; 34(2): 104-110
DOI: 10.1055/s-2002-19843
State of the Art Review

© Georg Thieme Verlag Stuttgart · New York

Ulcer and Gastritis

J.  C.  Y.  Wu1 , J.  J.  Y.  Sung1
  • 1Division of Gastroenterology, Dept. of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China
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Publication Date:
14 August 2002 (online)

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The literature on peptic ulcer and gastritis in 2000 again focused on the topics of Helicobacter pylori, nonsteroidal anti-inflammatory drugs (NSAIDs), and gastric cancer. New diagnostic tests for H. pylori infection have been evaluated, and rescue therapies for failed H. pylori eradication have been tested. The causal relationship between H. pylori infection and nonulcer dyspepsia, gastric cancer, gastroesophageal reflux disease, and NSAID-related ulcers remained heated topics of debate. In 2000, landmark clinical trials and meta-analyses were published addressing these issues. The role of endoscopy in managing nonulcer dyspepsia was better defined. The role of H. pylori eradication in NSAID/aspirin users was reexamined in high-risk patients. Clinical benefit was finally confirmed for specific inhibitors of cyclooxygenase-2 (COX-2). The millennium year turned out to be a very important one in the advancement of knowledge in this field.

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J. J. Y. Sung, M.D., Ph.D.

Division of Gastroenterology · Dept. of Medicine and Therapeutics

Prince of Wales Hospital · Chinese University of Hong Kong · Hong Kong · China

Fax: + 852-264-467824

Email: joesung@cuhk.edu.hk