Efficient Synthesis of Substituted Terphenyls by Suzuki Coupling Reaction [1]

Abstract

The Suzuki cross-coupling reactions of phenyl-1,4-dibor­onic acid bis-pinacol ester with a range of aryl halides are reported. The reaction proceeded smoothly, even with sterically hindered aryl halides, to give symmetrical terphenyls often quantitatively.

Key words

cross-coupling reaction - boronic esters - aryl halides - steric hindrance - terphenyls

1

Chaumeil H., Le Drian C. 31ème séminaire Hors-Ville d’Automne and 21st Regio Symposium in Organic and Bioorganic chemistry, 16-20th September 2001, Champery, Switzerland.

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1

Chaumeil H., Le Drian C. 31ème séminaire Hors-Ville d’Automne and 21st Regio Symposium in Organic and Bioorganic chemistry, 16-20th September 2001, Champery, Switzerland.