Reaction of 3-(1-Hydroxycyclohexyl)-2-propynenitrile with Tris[2-(4-pyridyl)ethyl]phosphine Oxide

Boris A. Trofimov; Ludmila V. Andriyankova; Svetlana I. Shaikhudinova; Tat’yana I. Kazantseva; Anastasiya G. Mal’kina; Andrei V. Afonin

doi:10.1055/s-2002-28516

SHORTPAPER

Reaction of 3-(1-Hydroxycyclohexyl)-2-propynenitrile with Tris[2-(4-pyridyl)ethyl]phosphine Oxide

Boris A. Trofimov*, Ludmila V. Andriyankova, Svetlana I. Shaikhudinova, Tat’yana I. Kazantseva, Anastasiya G. Mal’kina, Andrei V. Afonin
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Favorsky Street 1, 664033 Irkutsk, Russia
Fax: +7(3952)396046; e-Mail: bat@irioch.irk.ru;

Abstract

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Abstract

3-(1-Hydroxycyclohexyl)-2-propynenitrile reacts with tris[2-(4-pyridyl)ethyl]phosphine oxide to form mono-, bis- and tris{5-spirocyclohexyl-4-cyanomethylene-1,3-oxazolidine[3,2-a]-2-[4-(1,2-dihydropyridyl)]ethyl}phosphine oxides.

Key words

alkynes - pyridines - heterocycles - phosphorus - stereoselective synthesis

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References

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