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Int J Sports Med 2002; 23(4): 298-304
DOI: 10.1055/s-2002-29082
Training and Testing
© Georg Thieme Verlag Stuttgart · New York

Decrease in Oxygen Uptake at the End of a High-Intensity Submaximal Running in Humans

S.  Perrey1 , R.  Candau2 , G.  Y.  Millet3 , F.  Borrani2 , J.  D.  Rouillon1
  • 1Laboratoire des Sciences du Sport, UFR STAPS, Besançon, France
  • 2Laboratoire Sport, Santé, Développement, Montpellier, France
  • 3Groupe Analyse du Mouvement, UFR STAPS, Dijon, France
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Publication History



October 6, 2001

Publication Date:
14 May 2002 (online)

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Abstract

The purpose of the present study was to examine oxygen consumption (V˙O2) kinetics during severe-intensity running exercise through a four-phase model that considered a decrease in V˙O2 at the end of the exercise in light of previous research in which this decrease was only noticed. After determination of maximal oxygen consumption (V˙O2max), thirteen highly trained males performed a square-wave running to exhaustion at ~95 % of V˙O2max on a level treadmill. V˙O2 and ventilatory gas exchange variables were determined breath-by-breath. Computerised non-linear regression techniques incorporating exponential and linear terms were used to describe V˙O2 and ventilatory gas exchange variable responses. In contrast with the classical 3-component model that describes the increase in V˙O2 for severe-intensity exercise, we observed a 4th phase characterised by a significant decrease in V˙O2 before exhaustion (slope of V˙O2-time relationship significantly different from a zero value, p < 0.01) in 7 out of 13 subjects. Following a time delay of 31 ± 44 s after the decrease in V˙O2, a significant decrease of minute ventilation (V˙E) was present for 6 of the 7 subjects (p < 0.02). During the exercise for the subjects who decreased V˙E, a reduction of 288 ± 169 ml in tidal volume was associated with an increase of 10.2 ± 2.4 min-1 in breathing frequency. These data suggest that the respiratory system might be stressed more for some endurance-trained athletes. The specific link between reduced V˙O2 and reduced V˙E remains to be explored.

Key words

Oxygen uptake kinetics - V˙O2 slow component - breathing pattern - fatigue - mathematical modelling

References

  • 1 Andersen P, Saltin B. Maximal perfusion of skeletal muscle.  J Physiol. 1985;  366 233-249
    CrossrefPubMedSearch in Google Scholar
  • 2 Astrand P O, Saltin B. Oxygen uptake during the first minutes of heavy exercise.  J Appl Physiol. 1961;  16 971-976
    PubMedSearch in Google Scholar
  • 3 Barstow T J, Jones A M, Nguyen P H, Casaburi R. Influence of muscle type and pedal frequency on oxygen uptake kinetics of heavy exercise.  J Appl Physiol. 1996;  81 1642-1650
    CrossrefPubMedSearch in Google Scholar
  • 4 Bearden S E, Moffatt R J. V˙O2 kinetics and the O2 deficit in heavy exercise.  J Appl Physiol. 2000;  88 1407-1412
    PubMedSearch in Google Scholar
  • 5 Bernard O, Maddio F, Ouattara S, Jimenez C, Charpenet A, Melin B, Bittel J. Influence of the oxygen uptake slow component on the aerobic energy cost of high-intensity submaximal treadmill running in humans.  Eur J Appl Physiol. 1998;  78 578-585
    CrossrefPubMedSearch in Google Scholar
  • 6 Billat V, Renoux J C, Pinoteau J, Petit B, Koralsztein J P. Reproducibility of running time to exhaustion at V˙O2max in subelite runners.  Med Sci Sports Exerc. 1994;  26 254-257
    CrossrefPubMedSearch in Google Scholar
  • 7 Borrani F, Candau R, Millet G Y, Perrey S, Fuchslocher J, Rouillon J D. Is the V˙O2 slow component dependent on progressive recruitment of fast-twitch fibers in trained runners?.  J Appl Physiol. 2001;  90 2212-2220
    CrossrefPubMedSearch in Google Scholar
  • 8 Candau R, Belli A, Millet G Y, Georges D, Barbier B, Rouillon J D. Energy cost and running mechanics during a treadmill run to volitional exhaustion.  Eur J Appl Physiol. 1998;  77 479-485
    CrossrefPubMedSearch in Google Scholar
  • 9 Cibella F, Cuttitta G, Kayser B, Narici M, Romano S, Saibene F. Respiratory mechanics during exhaustive submaximal exercise at high altitude in healthy humans.  J Physiol. 1996;  494 881-890
    PubMedSearch in Google Scholar
  • 10 Coast J R, Rasmussen S A, Krause K M, O’Kroy J A, Loy R A, Rhodes J. Ventilatory work and oxygen consumption during exercise and hyperventilation.  J Appl Physiol. 1993;  74 793-798
    PubMedSearch in Google Scholar
  • 11 Dempsey J A, Hanson P G, Henderson K S. Exercise-induced arterial hypoxemia in healthy human subjects at sea level.  J Physiol. 1984;  355 161-175
    CrossrefPubMedSearch in Google Scholar
  • 12 Dempsey J A, Harms C A, Ainsworth D M. Respiratory muscle perfusion and energetics during exercise.  Med Sci Sports Exer. 1996;  28 1123-1128
    PubMedSearch in Google Scholar
  • 13 di Nocera F, Ferlazzo F. Resampling approach to statistical inference: bootstrapping from event-related potentials data.  Behav Res Methods, Instrum Comput. 2000;  32 111-119
    PubMedSearch in Google Scholar
  • 14 Efron B. Bootstrap methods: another look at the jacknife.  Ann Stat. 1979;  7 1-26
    CrossrefPubMedSearch in Google Scholar
  • 15 Gaesser G A, Poole D C. The slow component of oxygen uptake kinetics in humans.  In: Holloszy J (ed). Exer Sport Sci Rev Baltimore; Williams and Wilkins 1996 24: 35-70
    Search in Google Scholar
  • 16 Gallagher C G, Im Hof V, Younes M. Effect of inspiratory muscle fatigue on breathing pattern.  J Appl Physiol. 1985;  59 1152-1158
    PubMedSearch in Google Scholar
  • 17 Geyssant A, Dormois D, Barthelemy J C, Lacour J R. Lactate determination with the lactate analyser LA 640: a critical study.  Scand J Clin Lab Invest. 1985;  45 145-149
    PubMedSearch in Google Scholar
  • 18 Harms C A, Babcock M A, McClaran S R, Pegelow D F, Nickele G A, Nelson W B, Dempsey J A. Respiratory muscle work compromises leg blood flow during maximal exercise.  J Appl Physiol. 1997;  82 1573-1583
    PubMedSearch in Google Scholar
  • 19 Harms C A, Wetter T J, McClaran S R, Pegelow D F, Nickele G A, Nelson W B, Hanson P, Dempsey J A. Effects of respiratory muscle work on cardiac output and its distribution during maximal exercise.  J Appl Physiol. 1998;  85 609-618
    PubMedSearch in Google Scholar
  • 20 Howley E T, Basseet T , Welch H G. Criteria for maximal oxygen uptake: review and commentary.  Med Sci Sports Exerc. 1995;  27 1292-1301
    PubMedSearch in Google Scholar
  • 21 Johnson B D, Saupe K W, Dempsey J A. Mechanical constraints on exercise hyperpnea in endurance athletes.  J Appl Physiol. 1992;  73 874-886
    PubMedSearch in Google Scholar
  • 22 Johnson B D, Babcock M A, Suman O E, Dempsey J A. Exercise-induced diaphragmatic fatigue in healthy humans.  J Physiol. 1993;  460 385-405
    CrossrefPubMedSearch in Google Scholar
  • 23 Lamarra N, Whipp B J, Ward S A. Effect of interbreath fluctuations on characterising exercise gas exchange kinetics.  J Appl Physiol. 1987;  62 2003-2012
    PubMedSearch in Google Scholar
  • 24 Langsetmo I, Poole D C. V˙O2 recovery kinetics in the horse following moderate, heavy, and severe exercise.  J Appl Physiol. 1999;  86 1170-1177
    PubMedSearch in Google Scholar
  • 25 Millet G Y, Lepers R, Lattier G, Martin V, Babault N, Maffiuletti N. Influence of ultra-long-term fatigue on the oxygen cost of two types of locomotion.  Eur J Appl Physiol. 2000;  83 376-380
    CrossrefPubMedSearch in Google Scholar
  • 26 Nummela A, Rusko H. Time course of anaerobic and aerobic energy expenditure during short-term exhaustive running in athletes.  Int J Sports Med. 1995;  16 522-527
    PubMedSearch in Google Scholar
  • 27 Obert P, Cleziou C, Candau R, Courteix D, Lecoq A M, Guenon P. The slow component of O2 uptake kinetics during high-intensity exercise in trained and untrained prepurbertal children.  Int J Sports Med. 1999;  20 31-36
    PubMedSearch in Google Scholar
  • 28 Porszasz J, Barstow T J, Wasserman K. Evaluation of a symmetrically disposed Pitot tube flowmeter for measuring gas flow during exercise.  J Appl Physiol. 1994;  77 2659-2665
    PubMedSearch in Google Scholar
  • 29 Rice A J, Scroop G C, Thorton A T, McNaughton N S, Rogers K J, Chapman M J, Greville H W, Scicchitano , Gore C J. Arterial hypoxaemia in endurance athletes is greater during running than cycling.  Resp Physiol. 2000;  123 235-246
    PubMedSearch in Google Scholar
  • 30 Spengler C M, Knöpfli-Lenzi C, Birchler K, Trapletti A, Boutellier U. Breathing pattern and exercise endurance time after exhausting cycling or breathing.  Eur J Appl Physiol. 2000;  81 368-374
    CrossrefPubMedSearch in Google Scholar
  • 31 Sullivan M J, Knight J D, Higginbotham M B, Cobb F R. Relation between central and peripheral hemodynamics during exercise in patients with chronic heart failure.  Circulation. 1989;  80 769-781
    PubMedSearch in Google Scholar
  • 32 Taylor H L, Buskirk E, Henschel A. Maximal oxygen uptake as an objective measure of cardiorespiratory performance.  J Appl Physiol. 1955;  8 73-80
    PubMedSearch in Google Scholar
  • 33 Tonkonogi M, Harris B, Sahlin K. Mitochondrial oxidative function in human saponin-skinned muscle fibres: effects of prolonged exercise.  J Physiol. 1998;  510 279-286
    CrossrefPubMedSearch in Google Scholar
  • 34 Whipp B J, Ward S A, Lamarra N, Davis A, Wasserman K. Parameters of ventilatory and gas exchange dynamics during exercise.  J Appl Physiol. 1982;  52 1506-1513
    PubMedSearch in Google Scholar

Dr. S. Perrey

Faculté des sciences du sport · UPRES EA 2991

700 av du pic saint loup · 34090 Montpellier · France ·

Phone: +33 04 67 41 57 54

Fax: +33 04 67 41 57 50

Email: s.perrey@staps.univ-montp1.fr