An Expeditious One-Pot Synthesis of Thiiranes from α-Halo Ketones in Solvent­-Free Conditions Using Microwaves

Abstract

Thiiranes are obtained in excellent yields and with high diastereoselectivity upon microwave irradiation of a mixture of α-haloketones, O,O-diethyl hydrogen phosphorodithioate and alumina-supported sodium borohydride in solvent-free conditions.

α-haloketones - thiiranes - stereoselective synthesis - microwaves - solvent free - alumina supported

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