Subscribe to RSS
DOI: 10.1055/s-2002-35407
Isoflavonoide in der Behandlung der Hautalterung postmenopausaler Frauen
Isoflavonoids in the Treatment of Skin Aging in Postmenopausal WomenPublication History
Publication Date:
13 November 2002 (online)

Zusammenfassung
Präventive und kurative Maßnahmen zur Verzögerung der Hautalterung haben bei Frauen in fortgeschrittenen Lebensjahren einen besonderen Stellenwert. Phytoöstrogen-haltige Cremes bieten postmenopausalen Frauen ein wirksames sowie zugleich verträgliches und sicheres Instrument, um der hormonbedingten Hautalterung entgegenzutreten. Dies belegt eine kontrollierte Multizenterstudie an 234 Probandinnen.
Abstract
Preventive and therapeutic measures to retard skin aging in women are of outmost importance. Cremes containing phytoestrogens are convenient and safe tools to work against hormonal skin aging in postmenopausal women. This has been shown by a controlled multi-center study in 234 volunteers.
Literatur
- 1 Bazin R. et al . DensiScore® : a new tool for clinical evaluation of age dependent mechanical properties of female skin. Ann Dermatol Venerol. 2002; 129 1S371-1S602
- 2 Brincat M. Hormone replacement therapy and the skin. Maturitas. 2000; 35 107-117
- 3 Farnswoth N R, Bingel A S, Cordell G A, Crane F A, Fong H HS. Potential value of plants as sources of new antifertility agents. J Pharm Sci. 1975; 64 717-754
-
4 Hirayama T.
A large-scale cohort study on cancer risks by diet with special reference to the risk reducing effects of green-yellow vegetable consumption. In: Hayashi Y (Ed) Nutrition Cancer. Tokyo; Japanese Scientific Society Press 1986 - 5 Lacey J V Jr, Mink P J, Lubin J H, Sherman M E, Troisi R, Hertge P, Schatzkin A, Schairer C. Menopausal hormone replacement therapy and risk of ovarial cancer. JAMA. 2002; 288 334-341
- 6 Loewe S, Lange F, Spohr E. Über weibliche Sexualhormone. Biochem Zeitschr. 1927; 180 1-26
- 7 Markiewitz L, Garey J, Adlerkreutz H, Gurpide E. In vitro bioassay of nonsteroidal phytooestrogens. J Steroid Biochem Molec Biol. 1993; 45 399-405
- 8 Messina M. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer. 1994; 21 113-131
-
9 Noch nicht veröffentlichte Daten von Vichy Cosmetique Active Deutschland.
- 10 Punnonen R. Effect of castration and peroral estrogen therapy on the skin. Acta Obstet Gynecol Scand Suppl. 1972; 21 3-44
- 11 Rodriguez C, Patel A V, Calle E E, Jacob E J, Thun M J. Estrogen replacement therapy and ovarian cancer mortality in a large prospective study of US women. JAMA. 2001; 285 1460-1465
- 12 Rose D P, Boyar A P, Wynder E L. International comparisons of mortality rates for breast cancer, ovary, prostate and colon per capital food consumption. Cancer. 1986; 58 2363-2371
- 13 Schmidt J B, Spona J. Steroidrezeptoren in normaler Haut. Z Hautkr. 1986; 61 841-846
- 14 Schmidt J B, Binder M, Demschik G, Biegelmayer C, Reiner A. Treatment of skin aging with topical estrogens. Int J Dermatol. 1996; 35 669-674
- 15 Vanttinen K, Moravoca J. Transdermal absorption of phytoestrogens. Pharmazie. 2001; 56 711-717
- 16 Varani J, Fisher G, Kang S, Voorhees J J. Molecular mechanisms of intrinsic skin aging and retinoid-induced repair and reversal. J Invest Dermatol Symp Processings. 1998; 3 57-60
- 17 Wang T TY, Sathyamoorthy N, Phang J M. Molecular effects of genistein on estrogen receptor mediated pathways. Carcinogenesis. 1996; 17 271-275
PD Dr. med. Christiane Bayerl
Klinik für Dermatologie, Venerologie und Allergologie · Universitätsklinikum
Theodor-Kutzer-Ufer 1 - 3 · 68135 Mannheim
Email: christiane.bayerl@haut.ma.uni-heidelberg.de