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Planta Med 2003; 69(6): 582-584
DOI: 10.1055/s-2003-40646
Letter
© Georg Thieme Verlag Stuttgart · New York

A New Triterpene from Leandra chaetodon

Qinglin Zhang1 , Hala N. ElSohly1 , Xing-Cong Li1 , Larry A. Walker1 , 2
  • 1National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, Thad Cochran Research Center, School of Pharmacy, The University of Mississippi, University, MS, USA
  • 2Department of Pharmacology, School of Pharmacy, The University of Mississippi, University, MS, USA
Further Information

Publication History

Received: October 25, 2002

Accepted: February 15, 2003

Publication Date:
16 July 2003 (online)

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Abstract

A new triterpene compound (1), along with arjunolic acid, was isolated from an ethanol extract of the whole plant of Leandra chaetodon. Based on spectroscopic analysis, the structure of 1 was determined as 2α,6α- dihydroxybetulinic acid. Arjunolic acid showed inhibitory activity against Cryptococcus neoformans. (IC50 = 20 μg/mL).

References

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Dr. Hala N. ElSohly

National Center for Natural Products Research

School of Pharmacy

University of Mississippi

University

MS 38677

USA

Email: helsohly@olemiss.edu

Fax: +1-662-915-7062