Molecular Diversity of Tonghaosu: Synthesis of Lactam-Containing Tonghaosu Analogs

Abstract

A new type of tonghaosu analogs containing spiroketal and lactam functionality was synthesized from methyl 2-furoate and amino alcohols. The stereoselective control of spiroketal chirality was also explored.

Key words

tonghaosu analogs - antifeedant - lactam - spiroketalization - diastereoselective

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