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Synthesis 2004(1): 63-68  
DOI: 10.1055/s-2003-44366
PAPER
© Georg Thieme Verlag Stuttgart · New York

Indium(III) Chloride/Silica Gel-Promoted Facile and Rapid Cyclization of 2-Aminochalcones to 2-Aryl-2,3-dihydroquinolin-4(1H)-ones under Solvent-Free Conditions

K. Hemanth Kumar, D. Muralidharan, P. T. Perumal*
Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai-600 020, India
Fax: +91(44)4911589; e-Mail: ptperumal@hotmail.com;
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Publication History

Received 3 September 2003
Publication Date:
09 December 2003 (online)

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Abstract

A convenient environmentally friendly method for the cyclization of 2-aminochalcones to 2-aryl-2,3-dihydroquinolin-4(1H)-ones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent has been reported.

Key words

indium(III) chloride/silica gel - 2-aminochalcones - microwave - solvent-free conditions