Unexpected Addition of Methyl 3,3,3-Trifluoropyruvate to ‘Push-Pull’ Enamines Having a Methyl Group at α-Position

Abstract

The reaction of ‘push-pull’ enamines having a methyl group at the α-position with methyl 3,3,3-trifluoropyruvate was investigated. As a result, unexpected addition of pyruvate to methyl group was found and a set of polyfunctionalized β-dicarbonyl compounds was obtained. Possible mechanism of the reaction is discussed.

Key words

‘push-pull’ enamines - methyl 3,3,3-trifluoropyruvate - nucleophilic addition - ene reaction

References

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