Subscribe to RSS
DOI: 10.1055/s-2004-833500
Prospective Evaluation of Outcome Measures in Free-Flap Surgery
Publication History
Accepted: 1 April 2004
Publication Date:
09 September 2004 (online)
Free-flap failure is usually caused by venous or arterial thrombosis. In many cases, lack of experience and surgical delay also contribute to flap loss. The authors prospectively analyzed the outcome of 57 free flaps over a 28-month period (January, 1999 to April, 2001). The setting was a university hospital tertiary referral center. Anastomotic technique, ischemia time, choice of anticoagulant, and the grade of surgeon were recorded. The type of flap, medications, and co-morbidities, including preoperative radiotherapy, were also documented. Ten flaps were re-explored (17 percent). There were four cases of complete flap failure (6.7 percent) and five cases of partial failure (8.5 percent). In patients who received perioperative systemic heparin or dextran, there was no evidence of flap failure (p = .08). The mean ischemia time was similar in flaps that failed (95 ± 29 min) and in those that survived (92 ± 34 min). Also, the number of anastomoses performed by trainees in flaps that failed (22 percent), was similar to the number in flaps that survived (28 percent). Nine patients received preoperative radiotherapy, and there was complete flap survival in each case. This study reveals that closely supervised anastomoses performed by trainees may have a similar outcome to those performed by more senior surgeons. There was no adverse effect from radiotherapy or increased ischemia time on flap survival.
KEYWORDS
Free flap - anastomosis - failure rate - trainee - anticoagulation
REFERENCES
- 1 Khouri R K, Cooley B C, Kunselman A R et al.. A prospective study of microvascular free flap surgery and outcome. Plast Reconstr Surg. 1998; 102 711-721
- 2 Adams W P, Ansari M S, Hay M T et al.. Patency of different arterial and venous end-to-side microvascular techniques in a rat model. Plast Reconstr Surg. 2000; 105 156-161
- 3 Conrad M H, Adams Jr W P. Pharmacologic optimization of microsurgery in the new millennium. Plast Reconstr Surg. 2001; 108 2088-2096
- 4 Wong L, Im M J, Hoopes J E. Increased survival of island skin flaps by systemic heparin in rats. Ann Plast Surg. 1991; 26 221-226
- 5 Greenberg B M, Masem M, May Jr J W. Therapeutic value of intravenous heparin in microvascular surgery. An experimental vascular thrombosis study. Plast Reconstr Surg. 1988; 82 463-472
- 6 Vlastou C, Earle A S. Intraoperative heparin in replantation surgery: experimental study. Ann Plast Surg. 1983; 10 112-114
- 7 Yii N W, Evans G R, Miller M J et al.. Thrombolytic therapy: what is its role in free flap salvage?. Ann Plast Surg. 2001; 46 601-604
- 8 Muramatsu K, Shigetomi M, Ihara K, Kawai S, Doi K. Vascular complication in free tissue transfer to the leg. Microsurgery. 2001; 21 362-365
- 9 Wei F C, Demirkan F, Chen H C et al.. The outcome of failed free flaps in head and neck and extremity reconstruction: what is next in the reconstructive ladder?. Plast Reconstr Surg. 2001; 108 1154-1160
- 10 Maffi T R, Tran N V. Free tissue transfer experience at a county hospital. J Reconstr Microsurg. 2001; 17 431-433
- 11 Hallock G G. Impact of the successful flap but failed reconstruction on the true rate of success in free tissue transfers. J Reconstr Microsurg. 200; 16 589-592
- 12 Johnson P C, Barker J H. Thrombosis and antithrombotic therapy in microvascular surgery. Clin Plast Surg. 1992; 19 799-807
- 13 Cox G W, Runnels S, Hsu H S, Das S K. A comparison of heparinized saline irrigation solutions in a model of microvascular thrombosis. Br J Plast Surg. 1992; 45 345-348
- 14 Salemark L, Wieslander J B, Dougan P, Arnljots B. Studies of the antithrombotic effects of dextran 40 following microarterial trauma. Br J Plast Surg. 1991; 44 15-22
- 15 Zhang B, Wieslander J B. Dextran's antithrombotic properties in small arteries are not altered by low-molecular weight heparin or the fibrinolytic inhibitor tranexamic acid: an experimental study. Microsurgery. 1993; 14 289-295
- 16 Pomerance J, Truppa K, Bilos Z J et al.. Replantation and revascularisation of the digits in a community microsurgical practice. J Reconstr Microsurg. 1997; 13 163-170
- 17 Godina M. Preferential use of end-to-side arterial anastomoses in free flap transfers. Plast Reconstr Surg. 1979; 64 673-682
- 18 Dotson R JN, Bishop A T, Wood M B, Schroeder A. End-to-end versus end-to-side arterial anastomosis patency in microvascular surgery. Microsurgery. 1998; 18 125-128
- 19 Nam D A, Roberts III T L, Acland R D. An experimental study of end-to-side micovascular anastomosis. Surg Gynae Obstet. 1978; 147 339-342
- 20 Shaw W W, Ko C Y, Ahn C Y, Markowitz B L. Safe ischemia time in free flap surgery: a clinical study of contact-surface cooling. J Reconstr Microsurg. 1996; 12 421-424
John L KellyM.D. F.R.C.S. (Plast)
Department of Plastic Surgery, University College Hospital Galway
Newcastle, Road
Galway, Ireland