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Thorac Cardiovasc Surg 2005; 53(3): 168-172
DOI: 10.1055/s-2005-837539
Original Thoracic

© Georg Thieme Verlag KG Stuttgart · New York

Carcinoid Tumors of the Lung and Multimodal Therapy

D. Divisi1 , R. Crisci1
  • 1Department of Thoracic Surgery, University of L'Aquila, “G. Mazzini” Hospital, Teramo, Italy
Further Information

Publication History

Received November 4, 2004

Publication Date:
30 May 2005 (online)

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Abstract

Aim: To report our experience with bronchial carcinoids. Methods: From January 1990 to March 2003 we treated 42 such patients, 30 females and 12 males. All patients underwent preoperative total body computed tomography (CT), total body In-111 octreotide scintigraphy, and SPECT of the thorax, with evaluation of serum levels of CEA, CgA, NSE, and urinary 5-HIAA. Diagnosis was obtained in 28 patients with fibre-optic bronchoscopy and in 14 patients with CT-guided trans-thoracic needle biopsy. Results: There were 26 typical and 16 atypical carcinoids. 30 lobectomies, 5 bilobectomies, 6 wedge resections, and 1 pneumonectomy were carried out. The 3-year and the 5-year survival rates in the typical and atypical carcinoid groups were 100 % and 96 % vs. 81 % and 68 %, respectively (p < 0.001). Conclusions: Long-term survival is based on histological completeness of surgical treatment. Octreotide scintigraphy and SPECT document N1 and N2 precisely.

Key words

Neuroendocrine tumors - bronchial carcinoids - classification - (111In-DTPA-D-Phe1) octreotide scintigraphy - surgical therapy

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Dr. D. Divisi

Department of Thoracic Surgery, University of L'Aquila, “G. Mazzini” Hospital

Circonvallazione Ragusa 39

64100 Teramo

Italy

Phone: + 39861429482

Fax: + 39 8 61 21 16 26

Email: duilio.divisi@virgilio.it