Efficient One-Pot Synthesis of 1,2,3-Triazoles from Benzyl and Alkyl Halides

Abstract

An efficient one-pot method for the preparation of 1,2,3-triazoles by 1,3-dipolar cycloaddition of in situ generated azides and alkynes is presented. This facile method can be applied to benzyl or alkyl halides and pure products are isolated by simple filtration.

Key words

1,3-dipolar cycloadditon - click chemistry - 1,2,3-tri­azoles - one-pot synthesis

References

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11

Progress of the reaction can be monitored by TLC.