Synlett 2006(8): 1189-1192  
DOI: 10.1055/s-2006-939712
LETTER
© Georg Thieme Verlag Stuttgart · New York

Highly Enantioselective Pd-Catalyzed Asymmetric Hydrogenation of N-Diphenylphosphinyl Ketimines

You-Qing Wang, Yong-Gui Zhou*
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, P. R. of China
Fax: +86(411)84379220; e-Mail: ygzhou@dicp.ac.cn;
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Publication History

Received 16 November 2005
Publication Date:
05 May 2006 (online)

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Abstract

A variety of substituted N-diphenylphosphinyl imines were hydrogenated using Pd(CF3CO2)2/(S)-SEGPHOS as a catalyst with high enantioselectivities (86.7%-98.6% ee).