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DOI: 10.1055/s-2006-951385
© Georg Thieme Verlag KG Stuttgart · New York
Successful Treatment of Alcohol Withdrawal with Trazodone
Publication History
Received 18. 4. 2006
Revised 24. 7. 2006
Accepted 24. 7. 2006
Publication Date:
23 November 2006 (online)
Trazodone, a second generation antidepressant, is helpful in the treatment of lasting alcohol withdrawal symptoms, such as sleep disturbances and craving. We report a case suggesting that trazodone is also efficient for the treatment of the acute phase of alcohol withdrawal treatment. A 30-year-old male patient with severe alcohol withdrawal symptoms was successfully treated with an adjuvant administration of 600 mg trazodone per day, while he had remained symptomatic for several days under high doses of diazepam and clomethiazolum. Controlled trials with trazodone for this indication could be useful.
References
- 1 Berney P, Dayer-Daeniker I, Paschoud A, Schulz P. Nefazodone Withdrawal Syndrome Responds to the Administration of Trazodone. Pharmacopsychiatry. 2005; 38 41-68
- 2 Friedmann PD, Herman DS, Freedman S, Lemon SC, Ramsey S, Stein MD. Treatment of sleep disturbance in alcohol recovery: a national survey of addiction medicine physicians. J Addict Dis. 2003; 22 91-103
- 3 Janiri L, Hadjichristos A, Buonanno A. Adjuvant trazodone in the treatment of alcoholism: an open study. Alcohol Alcohol. 1998; 33 362-365
- 4 Le Bon O, Murphy JR, Staner L. Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: polysomnographic and clinical evaluations. J Clin Psychopharmacol. 2003; 23 377-383
- 5 Roccatagliata G, Albano C, Maffini M, Farelli S. Alcohol withdrawal syndrome: treatment with trazodone. Int Pharmacopsychiatry. 1980; 15 105-108
Correspondence
Laurence BorrasMD
University Hospital of Geneva·Department of Psychiatry
Consultation Secteur Eaux-Vives
36 Rue du XXXI Décembre
1207 Geneva
Switzerland
Phone: +41/22/382 31 03
Email: Laurence.Borras@hcuge.ch