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Planta Med 1998; 64(5): 448-450
DOI: 10.1055/s-2006-957478
Papers
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Isolation and Structure Elucidation of Alkaloids from the Bulb of Fritillaria wabuensis

Anjiang Zhang1 , Huayuan Wang2 , Xinyao Tang2 , Yong Zheng2 , Xiaochoi Yi2 , Kaibei Yu3
  • 1Department of Chemistry, Wenzhou Normal College, Wenzhou, Zhejiang, P. R. China
  • 2School of Pharmacy, West China University of Medical Sciences, Chengdu, P. R. China
  • 3Chengdu Institute of Organic Chemistry, Academia Sinica, Chengdu, P. R. China
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Publication History

1997

1997

Publication Date:
04 January 2007 (online)

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Abstract

Eight alkaloids were isolated from the bulb of Fritillaria wabuensis S. Y. Tang et S. C. Yueh (Liliaceae), which is efficacious against cough. Five of them are known and identified as imperialine (1), peimisine (2), ebeinone (3), isoverticine (4), and imperialine β-N-oxide (5), respectively. Alkaloid 5 is however, controversial. All the signals for both 1H- and 13C-NMR spectra of 5 were assigned unambigously by 2D NMR experiments, and 13C-NMR assignments previously described in the literature were revised. An X-ray structure of alkaloid 5 is presented.

Key words

2D NMR - Fritillaria wabuensis S. Y. Tang et S. C. Yueh - Liliaceae - imperialine β-N-oxide - alkaloid - 13C-NMR