Antibacterial and Antifungal Compounds from Kigelia pinnata

Oluwatoyin A. Binutu; Kayode E. Adesogan; Joseph I. Okogun

doi:10.1055/s-2006-957900

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Planta Med 1996; 62(4): 352-353
DOI: 10.1055/s-2006-957900

Letters

Antibacterial and Antifungal Compounds from Kigelia pinnata

Oluwatoyin A. Binutu¹ , Kayode E. Adesogan² , Joseph I. Okogun²

¹Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria
²Department of Chemistry, University of Ibadan, Ibadan, Nigeria

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1995

1996

Publication Date:
04 January 2007 (online)

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Abstract

A biologically monitored fractionation of the methanolic extracts of the root and fruits of Kigelia pinnata D. C. led to the isolation of the naphthoquinones kigelinone (1), iso-pinnatal (2), dehydro-α-lapachone (3), and lapachol (4) and the phenylpropanoids p-coumaric acid (5) and ferulic acid (6) as the compounds responsible for the observed antibacterial and antifungal activity of the root and kigelinone (1) and caffeic acid (7) from the fruits of this plant.