Constituents of Veltheimia viridifolia; I. Homoisoflavanones of the Bulbs*

Gudrun Amschler; August W. Frahm; Armin Hatzelmann; Ulrich Kilian; Dieter Müller-Doblies; Ulrike Müller-Doblies

doi:10.1055/s-2006-957964

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Planta Med 1996; 62(6): 534-539
DOI: 10.1055/s-2006-957964

Papers

Constituents of Veltheimia viridifolia; I. Homoisoflavanones of the Bulbs*

Gudrun Amschler¹ , August W. Frahm¹ , Armin Hatzelmann² , Ulrich Kilian² , Dieter Müller-Doblies³ , Ulrike Müller-Doblies³

¹Lehrstuhl für Pharmazeutische Chemie der Universität Freiburg, Hermann-Herder-Str. 9, D-79104 Freiburg i. Br., Germany
²Byk Gulden Pharmaceuticals, Department of Biochemistry/Pharmacology, Byk-Gulden-Str. 2, D-78467 Konstanz, Germany
³Herbarium BTU, Institut für Biologie, Fachbereich 14, Technische Universität Berlin, Franklin Str. 28-29, D-10587 Berlin, Germany

* Dedicated to Prof. Dr. Drs. h.c. H. Oelschläger on the occassion of 75th anniversary of his birthday.

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Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

The new homoisoflavanone R(-)-3-(4-hydroxybenzyl)-5-hydroxy-6,7,8-trimethoxychroman-4-one (1) was isolated from the petroleum ether and the diethyl ether extracts of the bulbs of Veltheimia viridifolia (Hyacinthaceae) together with the known homoisoflavanone muscomin (2). The structures of the compounds were elucidated by means of ¹H-NMR, 2D ¹H-¹H-COSY, ¹³C-NMR, HMQC, HMBC, mass, and CD spectra. Pharmacological testings of the new homoisoflavanone are reported.

Key words

Veltheimia viridifolia - Hyacinthaceae - homoisoflavanones - phosphodiesterase inhibitor activity