Inhibition of Lens Aldose Reductase by Biflavones from Ouratea spectabilis

Joana D'Arc Felício; Edlayne Gonçalez; Maria Maia Braggio; Luca Costantino; Albano Albasini; Arlete Paulino Lins

doi:10.1055/s-2006-958059

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Planta Med 1995; 61(3): 217-220
DOI: 10.1055/s-2006-958059

Paper

Inhibition of Lens Aldose Reductase by Biflavones from Ouratea spectabilis

Joana D'Arc Felício¹ , Edlayne Gonçalez¹ , Maria Maia Braggio¹ , Luca Costantino² , Albano Albasini² , Arlete Paulino Lins¹

¹Seção de Farmacologia, Instituto Biológico, Av. Cons. Rodrigues Alves 1252, 04014-002, São Paulo, S.P., Brasil
²Dipartimento di Scienze Farmaceutiche. Università degli Studi di Modena, Via Campi 183, I-41100 Modena, Italy

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Publication History

1994

1994

Publication Date:
04 January 2007 (online)

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Abstract

Two biflavonoids were isolated from the EtOH extract from leaves of Ouratea spectabilis. Their structures were established to be the novel 6,6″-bigenkwanin and 7,7″-dimethoxyagathisflavone on the basis of spectroscopic data. The inhibition of bovine lens aldose reductase exerted by these biflavones has been studied.

key words

Ouratea spectabilis - Ochnaceae - biflavonoids - aldose reductase