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Planta Med 1993; 59(3): 272-275
DOI: 10.1055/s-2006-959668
Paper

© Georg Thieme Verlag Stuttgart · New York

Cucurbitacins as Constituents of Wilbrandia ebracteata

Mareni Rocha Farias1 , 2 , Eloir Paulo Schenkel3 , Ralf Mayer2 , Gerhard Rücker2 , 4
  • 1From Farias, M. R. (1991) Thesis, Universität Bonn, Germany. New address: Departamento de Ciencias Farmaceuticas do Centro de Ciencias da Saude da Universidade Federal de Santa Catarina - UFSC, Campus Universitáario, Trindade, 88.049 Florianópolis, SC, Brazil
  • 2Pharmazeutisches Institut der Universität Bonn, Kreuzbergweg 26, D(W)-5300 Bonn 1, Federal Republic of Germany
  • 3Faculdade de Farmácia da Universidade Federal do Rio Grande do Sul - UFRGS, Av. Ipiranga 2752, 90.620 Porto Alegre, RS, Brazil.
  • 4Address for correspondence
Further Information

Publication History

1992

1992

Publication Date:
04 January 2007 (online)

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Abstract

The methanolic extract from the roots of Wilbrandia ebracteata afforded, in addition to the known dihydrocucurbitacins B and E, dihydroisocucurbitacin B, Cucurbitacins B, D, E, G, H, P, and 22-deoxycucurbi-tacin D, four new compounds whose structures were elucidated as (20R,24ξ)-3)3β,16α,20)24,25-pentahydroxy-10α-cucurbit-5-ene-2,11,22-trione (3-epi-isocucurbitacin G) (8), (20R,22ξ)-2β16a,20,22,25-pentahydroxy-10α-cucurbita-5,23t-diene-3,11-dione (13), (20R)-25-acetoxy-3,16α,20-trihydroxy-30-nor-2-(β-D-glucopyranosyloxy)-1,2,3,4,5,10-dehydrocucurbit-6-ene-11,22-dione (14), and dihydroisocucurbitacin B-3-glucoside (16).

Key words

Wilbrandia ebracteata - Cucurbitacins.