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Planta Med 1991; 57(5): 399-402
DOI: 10.1055/s-2006-960133
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© Georg Thieme Verlag Stuttgart · New York

Comparison of Anti-Lipid Peroxidative Effects of the Underground Parts of Notopterygium incisum and N. forbesii in Mice

Xiu-Wei Yang, Zhe-Ming Gu, Ben-Xiang Wang, Masao Hattori, Tsuneo Namba
  • Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan
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Publication History

1990

Publication Date:
05 January 2007 (online)

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Abstract

Intraperitoneal administration of CCl4 to mice led to significant increases of thiobarbituric acid-reactive substances (TBA-RS), free malondialdehyde (MDA), lipid conjugated dienes and fluorescent lipid peroxidation products in the liver. However, subchronic pretreatment with oral doses of the MeOH extract of either the undergroud part of Notopterygium incisum or that of N. forbesii appreciably suppressed the formation of CCl4-induced lipid peroxidation products. The suppressing potency was more remarkable in the former.

Key words

Anti-oxidant - CCl4-induced lipid peroxidation - Notopterygium forbesii - Notopterygium incisum