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Horm Metab Res 1991; 23(8): 392-394
DOI: 10.1055/s-2007-1003708
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Alterations of Lipid Metabolism in Men with Hypotestosteronemia

Melita Hromadová1 , T. Háčik1 , E. Malatinský2 , I. Riečanský3
  • 1Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava
  • 2Clinical of Urology, University School of Medicine, Comenius University, Bratislava
  • 3Institute of Cardiovascular Diseases, Bratislava, Czechoslovakia
Further Information

Publication History

1990

1991

Publication Date:
14 March 2008 (online)

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Summary

Studied relationship in serum concentration of testosterone and lipids in 35 men with a positive coronarographic finding and 30 sterile men, in comparison with a control group. From lipid parameters we determined serum concentration of cholesterol, triacylglycerols and apolipoprotein B, and lipid distribution in lipoprotein fractions.

Serum testosterone concentration was found decreased in both the group as against the controls. As to lipid parameters, cholesterol concentration was depressed in the high-density lipoprotein (HDL) fraction of both the clinical groups. As increased apolipoprotein B level was seen in men with the positive coronarographic finding.

The results point to a negative effect of lowered testosterone concentrations on lipid metabolism.

Key words

Oligospermia - Coronarosclerosis - Lipoproteins (VLDL, LDL, HDL, Cholesterol) - Triacylglycerols - Apolipoprotein-B - Testosterone