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Planta Med 1985; 51(4): 339-340
DOI: 10.1055/s-2007-969507
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© Georg Thieme Verlag Stuttgart · New York

Isolation and Hypoglycemic Activity of Ganoderans A and B, Glycans of Ganoderma lucidum Fruit Bodies[1]

Hiroshi Hikino2 , Chohachi Konno2 , Yoshiaki Mirin3 , Teruaki Hayashi3
  • 2Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan
  • 3Research Laboratory, Koshiro and Co., 1-10-13 Ina, Minoo, Osaka, Japan
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Publication History

1984

1985

Publication Date:
26 February 2007 (online)

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Abstract

A water extract of the Oriental crude drug “reishi”, the fruit bodies of Ganoderma lucidum, significantly decreased plasma sugar level in mice. Fractionation of the extract by monitoring the hypoglycemic activity afforded two glycans, ganoderans A and B. These glycans elicited remarkable hypoglycemic actions in normal and alloxan-induced hyperglycemic mice.

1 Antidiabetes drugs, Part 9. Also Part 91 in the validity of the Oriental medicines

1 Antidiabetes drugs, Part 9. Also Part 91 in the validity of the Oriental medicines