Lebermetastasen kolorektaler Karzinome - wie oft kann man operieren?

Zusammenfassung

Rezidivmetastasen kolorektaler Karzinome in der Leber sind häufig. Die erneut operative Therapie mit vollständiger Tumorentfernung ist anderen Therapieoptionen überlegen. 20 % der Patienten mit Rezidivmetastasen erfüllen die Voraussetzung für eine R 0-Resektion. Die Morbidität von Rezidiveingriffen entspricht der nach Ersteingriffen. Die 5-Jahres-Überlebensrate nach Rezidiveingriff schwankt zwischen 30 und 40 %. Häufig werden zusätzliche Eingriffe wegen extrahepatischer Rezidive erforderlich. Rezidivmetastasen in der Leber erfordern die interdisziplinäre Diskussion, um die für den Patienten optimale Therapie zu finden.

Abstract

Recurrent liver metastases of colorectal carcinoma are frequent. The repeat hepatectomy is superior to other therapeutic options. In about 20 % of patients with recurrent liver metastases a complete resection (R 0) is possible. The morbidity of repeat hepatectomy is similar to that of first hepatectomy. The 5-year survival rate after repeat hepatectomy ranges between 30 and 40 %. Often in the follow-up additional operations become necessary for extrahepatic recurrencies. For determination of the optimal therapy an interdisciplinary approach must be chosen.

Schlüsselwörter

Rezidivlebermetastase - operative Therapie

Key words

recurrent liver metastasis - operative therapy

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