Neonatal Echovirus Encephalitis with White Matter Necrosis

J. Haddad; J. Messer; J. P. Gut; D. Chaigne; D. Christmann; D. Willard

doi:10.1055/s-2008-1071500

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Neuropediatrics 1990; 21(4): 215-217
DOI: 10.1055/s-2008-1071500

Case report

Neonatal Echovirus Encephalitis with White Matter Necrosis

J. Haddad¹ , J. Messer¹ , J. P. Gut² , D. Chaigne¹ , D. Christmann³ , D. Willard¹

¹Service de néonatologie, CHU de Hautepierre, F-67098 Strasbourg Cedex France
²Laboratoire de Virologie et INSERM U74, Faculté de Médecine de Strasbourg, France
³Radiopédiatrie - Radiologie 2, CHU de Hautepierre, F-67098 Strasbourg Cedex, France

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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

The authors report a case of neonatal echovirus encephalitis associated with white matter necrosis. The pattern of illness in the neonatal period was diphasic, marked by hyperthermia and the occurrence of seizures. Echovirus was recovered from the cerebrospinal fluid. Cerebral magnetic resonance imaging (MRI) performed at one month of age showed right periventricular white matter necrosis. The infant exhibited mild left hemiparesis. Cerebral MRI at 6 months of age showed a delay in myelination in the right hemisphere. Echovirus encephalitis in the neonate can cause brain damage.

Key words

Echovirus encephalitis - Newborn - Brain damage - MRI