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Planta Med 2008; 74(10): 1291-1294
DOI: 10.1055/s-2008-1081297
Natural Products Chemistry
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Cucurbitane-Type Triterpene Glycosides from the Fruits of Momordica charantia

Yi Liu1 , Zulfiqar Ali1 , Ikhlas A. Khan1 , 2
  • 1National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, Mississippi, USA
  • 2Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi, USA
Further Information

Publication History

Received: March 5, 2008 Revised: May 19, 2008

Accepted: May 23, 2008

Publication Date:
11 July 2008 (online)

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Abstract

Phytochemical investigation of the fruits of Momordica charantia resulted in the isolation and characterization of two new (1 and 2) and eight known cucurbitane-type triterpene glycosides and one cucurbitane-type triterpene. The glycosides (7β,25-dimethoxycucurbita-5(6),23(E)-dien-19-al 3-O-β-D-allopyranoside (1); 25-methoxycucurbita-5(6),23(E)-dien-19-ol 3-O-β-D-allopyranoside (2); momordicosides A, F1, F2, G, K, and L; and goyaglycoside-c and goyaglycoside-d) and the triterpene [3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al] were characterized by physical, chemical, and spectroscopic techniques, including 1D- and 2D-NMR as well as by comparison with the reported data.

Key words

Momordica charantia - Cucurbitaceae - cucurbitane-type triterpene glycosides

References

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Ikhlas A. Khan

National Center for Natural Products Research

University of Mississippi

University

Mississippi 38677

USA

Phone: +1-662-915-7821

Fax: +1-662-915-7989

Email: ikhan@olemiss.edu

    www.thieme-connect.de/ejournals/toc/plantamedica