Primary diffuse large B-cell non-hodgkin's lymphoma of the thoracic spine presented initially as an epigastric pain

Fakhr Fakhouri; Nihad Shoumal; Batoul Obeid; Ayman Alkhoder

doi:10.4103/ajns.AJNS_300_19

Asian Journal of Neurosurgery, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(01): 162-164
DOI: 10.4103/ajns.AJNS_300_19

Case Report

Primary diffuse large B-cell non-hodgkin's lymphoma of the thoracic spine presented initially as an epigastric pain

Autor*innen

Fakhr Fakhouri

Department of Neurosurgery, Krankenhaus der Barmherzigen Brüder, Trier
Nihad Shoumal

¹Department of Neurosurgery, Aleppo University Hospital, Aleppo
Batoul Obeid

²Department of Pathology, Aleppo University Hospital, Aleppo
Ayman Alkhoder

³Department of Medicine, Emory University School of Medicine, Atlanta, GA

Abstract

Non-Hodgkin's lymphoma (NHL) compromises the vast majority of lymphomas and predominantly takes on the form of B-cell lymphomas. More specifically, 30% of all newly diagnosed cases of NHL in the United States (US) are of diffuse large B-cell lymphoma (DLBCL) type, making it the most prevalent form of NHL in the US. Arising from either nodal or extra-nodal lymphatic tissue origin, DLBCL is an aggressive tumor which is fatal if left untreated. Primary central nervous system lymphoma is rare; however, when diagnosed, it presents as a DLBCL in 90% of patients. Herein, we present an elderly male complaining initially of acute epigastric pain but soon afterward developed acute spinal cord compressive symptoms; subsequently, it was found to be caused by a primary DLBCL diagnosed in the thoracic spinal cord. This case report presents a rare condition with unexpected initial presentation, and we attempt to illustrate the importance of early detection and treatment of DLBCL in attaining more favorable prognostic and survival rates among patients. Written consent was obtained from the patient after reading a written summary of the case report. This consent was checked and approved from the Scientific Board of the University of Aleppo.

Key-words:

Diffuse large B-cell lymphoma - epidural mass lesion - epigastric pain - non-Hodgkin's lymphoma - spinal tumor

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Referenzen

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