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CC BY-NC-ND 4.0 · South Asian J Cancer 2020; 09(01): 59-61
DOI: 10.4103/sajc.sajc_246_19
ORIGINAL ARTICLE: Supportive Care and Others

Role of Cresp® in the management of chemotherapy-induced anemia in cancer patients: A real-world clinical practice audit

Ghanshyam Biswas
Department of Medical Oncology, Sum Hospital, Bhubaneswar, Odisha
,
Avinash Pandey
Department of Medical Oncology, RCC, Patna, Bihar
,
Nikhil Ghadyalpatil
Department of Medical Oncology, Yashoda Hospital, Secunderabad, Telangana
,
Nilesh Lokeshwar
Department of Medical Oncology, Asian Cancer Institute, Mumbai, Maharashtra
,
Boben Thomas
Department of Medical Oncology, Kerala Institute of Medical Sciences, Trivandrum, Kerala
,
Anita Ramesh
Department of Medical Oncology, Apollo Specialty Hospital, Chennai, Tamil Nadu
,
Yogesh Arora
Department of Medical Oncology, Mohandai Oswal Hospital, Ludhiana, Punjab
,
Chandragouda Dodagoudar
Department of Medical Oncology, BLK Superspeciality Hospital, Delhi, NCR
,
Vibha Naik
Department of Medical Oncology, Naik Hospital, Baroda, Gujarat
,
Ashish Joshi
Department of Medical Oncology, Mumbai Oncocare Center, Mumbai, Maharashtra
,
Indranil Ghosh
Department of Medical Oncology, Apollo Hospital, Kolkata, West Bengal
,
Rakesh Roy
Department of Pain and Palliative Care, Saroj Gupta Cancer Hospital, Kolkata, West Bengal
,
Medhi Kunjahari
Department of Medical Oncology, Batra Cancer Center, Delhi, NCR
,
Tejinder Singh
Department of Medical Oncology, Fortis Hospital, Mumbai, Maharashtra
,
Palanki Dattatreya Satya
Department of Medical Oncology, Omega Hospital, Hyderabad, Telangana
,
Sachin Hingmire
Department of Medical Oncology, Deenanath Mangeshkar Hospital, Pune, Maharashtra
,
Purvish M. Parikh
Department of Medical Oncology, Shalby Cancer and Research Institute, Ahmedabad, Gujarat
› Author Affiliations Financial support and sponsorship: Nil.
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Abstract

Introduction: Anemia is a common, underestimated problem in cancer patients receiving myelosuppressive chemotherapy and has significant adverse effect on the quality of life and outcome. Darbepoetin has been shown to be effective in this setting, but controversy surrounds it actual use. Methods: We analyzed prospectively collected clinical practice data of patients receiving darbepoetin in a real-world setting for this retrospective audit. Patients with baseline hemoglobin (Hb) of <11 g/dl were included in this analysis. Their medical records were audited using a predetermined 35-point pro forma. Results: There were a total of 274 patients with advanced cancer receiving myelosuppressive chemotherapy who had baseline Hb <11 g/dl and who were given darbepoetin. Head-and-neck squamous cell carcinoma, lung cancer, and breast cancer were the most common cancers. Their median baseline Hb was 8.9 g/dl which rose to 11.2 g/dl at the end of commenced therapy, along with improved symptomatology. There were no new toxicities, and only two patients required discontinuation of darbepoetin due to toxicity. Conclusion: Darbepoetin is safe and effective in the prevention and management of anemia among patients receiving myelosuppressive chemotherapy.

Key words

Hemoglobin - India - prophylaxis - quality of life - quality of life


Publication History

Article published online:
14 December 2020

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