Download PDF
Bae, Yoon-Soo Cindy et al.: 2023 Procedural Dermatology: Postresidency and Fellowship Compendium, Volume 2 DOI: 10.1055/b-0043-196754

16 Soft-Tissue Augmentation with Dermal Fillers

More Information

Book

Editors: Bae, Yoon-Soo Cindy; Ciocon, David H.

Authors: Bae, Gee Young; Bernstein, Leonard J.; Boker, Andreas; Borash, Jordan; Bosley, Rawn; Brauer, Jeremy A.; Brown, Wilfred; Callaghan, Daniel; Chesnut, Cameron; Christman, Mitalee P.; Criscito, Maressa C.; Ebersole, Trina G.; Emer, Jason; Fabi, Sabrina Guillen; Fazzalari, Amanda; Friedman, Adam; Friedmann, Daniel P.; Geronemus, Roy G.; Goldberg, David J.; Gordon, Samantha; Graber, Emmy M.; Hazan, Ezra; Kent, Rhett A.; Khorasani, Hooman; Lederhandler, Margo H.; Lee, Austin; Li, Monica K.; Lin, Richard L.; Lipp, Michael B.; MacGregor, Jennifer L.; Mann, Margaret; Mehrabi, Joseph N.; Mishra, Vineet; Moak, Teri N.; Morton, Laurel M.; Murgia, Robert D.; Murphy, Emily C.; Paul, Benjamin Curman; Robinson, Deanne Mraz; Rokhsar, Cameron; Saedi, Nazanin; Scott, Jeffrey F.; Shridharani, Sachin M.; Soon, Seaver L.; Steele, Robert Blake; Steuer, Alexa B.; Tamashunas, Nina Lucia; Tan, Andrea; Tisch, Grace M.; Wang, Jordan V.; Weiss, Robert; Yeh, Lindsey; Zumwalt, Michael

Title: Procedural Dermatology: Postresidency and Fellowship Compendium, Volume 2

Print ISBN: 9783132424074; Online ISBN: 9783132437142; Book DOI: 10.1055/b000000254

1. Edition © 2023. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart,

Subjects: Dermatology;Allergology

Thieme Clinical Collections (English Language)



 
Andreas Boker

Summary

Soft-tissue augmentation with injectable fillers is a procedure being performed with increasing popularity. Knowledge of the available materials and their properties, a solid understanding of relevant facial anatomy, and proper injection technique are all crucial to ensure safe treatments and optimize patient outcomes.

Key words

soft tissue augmentation - facial contouring - dermal fillers - hyaluronic acids gels - calcium hydroxyapatite - poly-L-lactic acid
 
  • 2 American Society of Plastic Surgeons. Plastic Surgery Statistics Report. Arlinton Heights, IL: American Society of Plastic Surgeons National Clearinghouse; 2018
  • 3 Sinno S, Mehta K, Reavey PL, Simmons C, Stuzin JM. Current trends in facial rejuvenation: an assessment of ASPS members’ use of fat grafting during face lifting.. Plast Reconstr Surg 2015; 136 (1) 20e-30e PubMed (PMID: 26111329)
    PubMedGoogle Scholar
  • 4 Kablik J, Monheit GD, Yu L, Chang G, Gershkovich J. Comparative physical properties of hyaluronic acid dermal fillers.. Dermatol Surg 2009; 35 (Suppl. Suppl 1) 302-312 PubMed (PMID: 19207319)
    PubMedGoogle Scholar
  • 5 Tzellos TG, Klagas I, Vahtsevanos K et al. Extrinsic ageing in the human skin is associated with alterations in the expression of hyaluronic acid and its metabolizing enzymes.. Exp Dermatol 2009; 18 (12) 1028-1035 PubMed (PMID: 19601984)
    PubMedGoogle Scholar
  • 6 U.S. Food and Drug Administration. Dermal Fillers Approved by the Center for Devices and Radiological Health. 2018. Available at: https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/CosmeticDevices/ucm619846.htm#approved
  • 7 Santoro S, Russo L, Argenzio V, Borzacchiello A. Rheological properties of cross-linked hyaluronic acid dermal fillers.. J Appl Biomater Biomech 2011; 9 (2) 127-136 PubMed (PMID: 22065390)
    PubMedGoogle Scholar
  • 9 Artzi O, Loizides C, Verner I, Landau M. Resistant and recurrent late reaction to hyaluronic acid-based gel.. Dermatol Surg 2016; 42 (1) 31-37 PubMed (PMID: 26655699)
    PubMedGoogle Scholar
  • 10 Bhojani-Lynch T. Late-onset inflammatory response to hyaluronic acid dermal fillers.. Plast Reconstr Surg Glob Open 2017; 5 (12) e1532 PubMed (PMID: 29632758)
    PubMedGoogle Scholar
  • 11 Berlin AL, Hussain M, Goldberg DJ. Calcium hydroxylapatite filler for facial rejuvenation: a histologic and immunohistochemical analysis.. Dermatol Surg 2008; 34 (Suppl. Suppl 1) S64-S67 PubMed (PMID: 18547184)
    PubMedGoogle Scholar
  • 12 Shumaker PR, Sakas EL, Swann MH, Greenway Jr HT. Calcium hydroxylapatite tissue filler discovered 6 years after implantation into the nasolabial fold: case report and review.. Dermatol Surg 2009; 35 (Suppl. Suppl 1) 375-379 PubMed (PMID: 19207328)
    PubMedGoogle Scholar
  • 13 Feeney JN, Fox JJ, Akhurst T. Radiological impact of the use of calcium hydroxylapatite dermal fillers.. Clin Radiol 2009; 64 (9) 897-902 PubMed (PMID: 19664480)
    PubMedGoogle Scholar
  • 15 Gogolewski S, Jovanovic M, Perren SM, Dillon JG, Hughes MK. Tissue response and in vivo degradation of selected polyhydroxyacids: polylactides (PLA), poly(3-hydroxybutyrate) (PHB), and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB/VA).. J Biomed Mater Res 1993; 27 (9) 1135-1148 PubMed (PMID: 8126012)
    PubMedGoogle Scholar
  • 16 Bartus C, William Hanke C, Daro-Kaftan E. A decade of experience with injectable poly-L-lactic acid: a focus on safety.. Dermatol Surg 2013; 39 (5) 698-705 PubMed (PMID: 23379657)
    PubMedGoogle Scholar
  • 17 Lemperle G, Knapp TR, Sadick NS, Lemperle SM. ArteFill permanent injectable for soft tissue augmentation: I. Mechanism of action and injection techniques.. Aesthetic Plast Surg 2010; 34 (3) 264-272 PubMed (PMID: 19787394)
    PubMedGoogle Scholar
  • 18 Joseph JH, Shamban A, Eaton L et al. Polymethylmethacrylate collagen gel-injectable dermal filler for full face atrophic acne scar correction.. Dermatol Surg 2019; 45 (12) 1558-1566 PubMed (PMID: 30829754)
    PubMedGoogle Scholar
  • 19 Medeiros CC, Cherubini K, Salum FG, de Figueiredo MA. Complications after polymethylmethacrylate (PMMA) injections in the face: a literature review.. Gerodontology 2014; 31 (4) 245-250 PubMed (PMID: 23464838)
    PubMedGoogle Scholar
  • 22 Cotofana S, Fratila AA, Schenck TL, Redka-Swoboda W, Zilinsky I, Pavicic T. The anatomy of the aging face: a review.. Facial Plast Surg 2016; 32 (3) 253-260 PubMed (PMID: 27248022)
    PubMedGoogle Scholar
  • 23 Glaser DA, Lambros V, Kolodziejczyk J, Magyar A, Dorries K, Gallagher CJ. Relationship between midface volume deficits and the appearance of tear troughs and nasolabial folds.. Dermatol Surg 2018; 44 (12) 1547-1554 PubMed (PMID: 30379685)
    PubMedGoogle Scholar
  • 24 Hexsel D, Soirefmann M, Porto MD, Siega C, Schilling-Souza J, Brum C. Double-blind, randomized, controlled clinical trial to compare safety and efficacy of a metallic cannula with that of a standard needle for soft tissue augmentation of the nasolabial folds.. Dermatol Surg 2012; 38 (2) 207-214 PubMed (PMID: 22092962)
    PubMedGoogle Scholar
  • 25 Percec I, Bertucci V, Solish N, Wagner T, Nogueira A, Mashburn J. An objective, quantitative, dynamic assessment of hyaluronic acid fillers that adapt to facial movement.. Plast Reconstr Surg 2020; 145 (2) 295e-305e PubMed (PMID: 31985621)
    PubMedGoogle Scholar
  • 26 Carruthers A, Carruthers J. Evaluation of injectable calcium hydroxylapatite for the treatment of facial lipoatrophy associated with human immunodeficiency virus.. Dermatol Surg 2008; 34 (11) 1486-1499 PubMed (PMID: 18811715)
    PubMedGoogle Scholar
  • 27 Bassichis B, Blick G, Conant M et al. Injectable poly-L-lactic acid for human immunodeficiency virus-associated facial lipoatrophy: cumulative year 2 interim analysis of an open-label study (FACES).. Dermatol Surg 2012; 38 (7, Pt 2) 1193-1205 PubMed (PMID: 22759256)
    PubMedGoogle Scholar
  • 28 Wong CH, Hsieh MKH, Mendelson B. The tear trough ligament: anatomical basis for the tear trough deformity.. Plast Reconstr Surg 2012; 129 (6) 1392-1402 PubMed (PMID: 22634656)
    PubMedGoogle Scholar
  • 29 Scheuer III JF, Sieber DA, Pezeshk RA, Gassman AA, Campbell CF, Rohrich RJ. Facial danger zones: techniques to maximize safety during soft-tissue filler injections.. Plast Reconstr Surg 2017; 139 (5) 1103-1108 PubMed (PMID: 28445360)
    PubMedGoogle Scholar
  • 30 Breithaupt AD, Jones DH, Braz A, Narins R, Weinkle S. Anatomical basis for safe and effective volumization of the temple.. Dermatol Surg 2015; 41 (Suppl. Suppl 1) S278-S283 PubMed (PMID: 26618454)
    PubMedGoogle Scholar
  • 31 Reece EM, Pessa JE, Rohrich RJ. The mandibular septum: anatomical observations of the jowls in aging-implications for facial rejuvenation.. Plast Reconstr Surg 2008; 121 (4) 1414-1420 PubMed (PMID: 18349664)
    PubMedGoogle Scholar
  • 33 Vanaman Wilson MJ, Jones IT, Butterwick K, Fabi SG. Role of nonsurgical chin augmentation in full face rejuvenation: a review and our experience.. Dermatol Surg 2018; 44 (7) 985-993 PubMed (PMID: 29309340)
    PubMedGoogle Scholar
  • 34 Juhász MLW, Marmur ES. Examining the efficacy of calcium hydroxylapatite filler with integral lidocaine in correcting volume loss of the jawline: a pilot study.. Dermatol Surg 2018; 44 (8) 1084-1093 PubMed (PMID: 29677018)
    PubMedGoogle Scholar
  • 35 Beer K, Glogau RG, Dover JS et al. A randomized, evaluator-blinded, controlled study of effectiveness and safety of small particle hyaluronic acid plus lidocaine for lip augmentation and perioral rhytides.. Dermatol Surg 2015; 41 (Suppl 1) S127-S136 PubMed (PMID: 29677018)
    PubMedGoogle Scholar
  • 37 Heidekrueger PI, Juran S, Szpalski C, Larcher L, Ng R, Broer PN. The current preferred female lip ratio.. J Craniomaxillofac Surg 2017; 45 (5) 655-660 PubMed (PMID: 28318919)
    PubMedGoogle Scholar
  • 39 Goldman MP, Moradi A, Gold MH et al. Calcium hydroxylapatite dermal filler for treatment of dorsal hand volume loss: results from a 12-month, multicenter, randomized, blinded trial.. Dermatol Surg 2018; 44 (1) 75-83 PubMed (PMID: 28562435)
    PubMedGoogle Scholar
  • 40 Dierickx C, Larsson MK, Blomster S. Effectiveness and safety of acne scar treatment with nonanimal stabilized hyaluronic acid gel.. Dermatol Surg 2018; 44 (Suppl. Suppl 1) S10-S18 PubMed (PMID: 30358630)
    PubMedGoogle Scholar
  • 41 Sito G, Marlino S, Santorelli A. Use of Macrolane VRF 30 in emicircumferential penis enlargement.. Aesthet Surg J 2013; 33 (2) 258-264 PubMed (PMID: 23388646)
    PubMedGoogle Scholar
  • 43 Tansatit T, Apinuntrum P, Phetudom T. Facing the worst risk: confronting the dorsal nasal artery, implication for non-surgical procedures of nasal augmentation.. Aesthetic Plast Surg 2017; 41 (1) 191-198 PubMed (PMID: 28032167)
    PubMedGoogle Scholar
  • 44 DeFatta RJ, Krishna S, Williams III EF. Pulsed-dye laser for treating ecchymoses after facial cosmetic procedures.. Arch Facial Plast Surg 2009; 11 (2) 99-103 PubMed (PMID: 19289681)
    PubMedGoogle Scholar
  • 45 Beleznay K, Carruthers JD, Humphrey S, Jones D. Avoiding and treating blindness from fillers: a review of the world literature.. Dermatol Surg 2015; 41 (10) 1097-1117 PubMed (PMID: 26356847)
    PubMedGoogle Scholar
  • 46 Beleznay K, Carruthers JDA, Humphrey S, Carruthers A, Jones D. Update on avoiding and treating blindness from fillers: a recent review of the world literature.. Aesthet Surg J 2019; 39 (6) 662-674 PubMed (PMID: 30805636)
    PubMedGoogle Scholar
  • 47 DeLorenzi C. New high dose pulsed hyaluronidase protocol for hyaluronic acid filler vascular adverse events.. Aesthet Surg J 2017; 37 (7) 814-825 PubMed (PMID: 28333326)
    PubMedGoogle Scholar
  • 49 Chesnut C. Restoration of visual loss with retrobulbar hyaluronidase injection after hyaluronic acid filler.. Dermatol Surg 2018; 44 (3) 435-437 PubMed (PMID: 28877147)
    PubMedGoogle Scholar
  • 50 Paap MK, Milman T, Ugradar S, Silkiss RZ. Assessing retrobulbar hyaluronidase as a treatment for filler-induced blindness in a cadaver model.. Plast Reconstr Surg 2019; 144 (2) 315-320 PubMed (PMID: 31348334)
    PubMedGoogle Scholar
  • 51 Carey W, Weinkle S. Retraction of the plunger on a syringe of hyaluronic acid before injection: are we safe?. Dermatol Surg 2015; 41 (Suppl. Suppl 1) S340-S346 PubMed (PMID: 26618462)
    PubMedGoogle Scholar
  • 52 Douse-Dean T, Jacob CI. Fast and easy treatment for reduction of the Tyndall effect secondary to cosmetic use of hyaluronic acid.. J Drugs Dermatol 2008; 7 (3) 281-283 PubMed (PMID: 18380210)
    PubMedGoogle Scholar
  • 53 Robinson DM. In vitro analysis of the degradation of calcium hydroxylapatite dermal filler: a proof-of-concept study.. Dermatol Surg 2018; 44 (Suppl. Suppl 1) S5-S9 PubMed (PMID: 30358629)
    PubMedGoogle Scholar
  • 54 Ibrahim O, Overman J, Arndt KA, Dover JS. Filler nodules: inflammatory or infectious? A review of biofilms and their implications on clinical practice.. Dermatol Surg 2018; 44 (1) 53-60 PubMed (PMID: 28538034)
    PubMedGoogle Scholar
  • 55 Kadouch JA, Kadouch DJ, Fortuin S, van Rozelaar L, Karim RB, Hoekzema R. Delayed-onset complications of facial soft tissue augmentation with permanent fillers in 85 patients.. Dermatol Surg 2013; 39 (10) 1474-1485 PubMed (PMID: 24090257)
    PubMedGoogle Scholar
  • 56 Goulart JM, High WA, Goldenberg G. Evidence of calcium hydroxylapatite migration: distant nodule formation in the setting of concurrent injection with nonanimal stabilized hyaluronic acid.. J Am Acad Dermatol 2011; 65 (2) e65-e66 PubMed (PMID: 21763560)
    PubMedGoogle Scholar
  • 57 Vleggaar D, Fitzgerald R, Lorenc ZP. Understanding, avoiding, and treating potential adverse events following the use of injectable poly-L-lactic acid for facial and nonfacial volumization.. J Drugs Dermatol 2014; 13 (4) (Suppl. Suppl) s35-s39 PubMed (PMID: 24719076)
    PubMedGoogle Scholar
  • 58 Sadeghpour M, Quatrano NA, Bonati LM, Arndt KA, Dover JS, Kaminer MS. Delayed-onset nodules to differentially crosslinked hyaluronic acids: comparative incidence and risk assessment.. Dermatol Surg 2019; 45 (8) 1085-1094 PubMed (PMID: 30789508)
    PubMedGoogle Scholar
  • 59 Artzi O, Cohen JL, Dover JS et al. Delayed inflammatory reactions to hyaluronic acid fillers: a literature review and proposed treatment algorithm.. Clin Cosmet Investig Dermatol 2020; 13: 371-378 PubMed (PMID: 32547150)
    PubMedGoogle Scholar
  • 60 Aguilera SB, Aristizabal M, Reed A. Successful treatment of calcium hydroxylapatite nodules with intralesional 5-fluorouracil, dexamethasone, and triamcinolone.. J Drugs Dermatol 2016; 15 (9) 1142-1143 PubMed (PMID: 27602980)
    PubMedGoogle Scholar