5.1.29 Product Subclass 29: Silylated Germanes

Abstract

This chapter is focussed on the preparation of silylated germanes by silicon–germanium bond formation, and the applications of these compounds in organic synthesis. The synthetic methods are organized according to the reaction type used for the silicon–germanium bond formation. The discussion begins with the reductive coupling of silicon and germanium electrophiles, a Wurtz-type coupling reaction, which is a workhorse of heavier group 14 synthesis. This is followed by a presentation of reactions of such electrophiles with anionic germanium or silicon compounds, allowing for the synthesis of more complicated catenates. Then, the formation of silylated germanes by insertion of germylenes or silylenes into reactive group 14–main group element bonds is described. This is followed by a presentation of silicon–germanium bond formation by Lewis acid catalyzed rearrangement reactions. The chapter concludes with a discussion of the applications of silylated germanes in organic synthesis.

Key words

silanes - germanes - silagermanes - group 14 - silyl anions - germyl anions - Wurtz-type coupling - silylenes - germylenes

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