10.17 Benzo[b]phospholes

R. A. Aitken 

Abstract

This chapter is a complete revision and update of the earlier Science of Synthesis contribution from 2000 describing methods for the synthesis of benzo[b]phospholes. About half of the references cited describe newer methods reported between 2000 and 2021 and, as well as extensions to the previously described approaches, several completely new approaches are included. Among the strategies covered are reactions of metalated phenylalkyne derivatives with phosphorus halides, cyclizations of (2-alkynylphenyl)phosphorus compounds, direct reactions of phenylphosphorus compounds with alkynes, and aromatization of dihydro derivatives. In addition, the initially obtained compounds can be converted into a variety of derivatives by modification at phosphorus by oxidation, substitution, or reduction.

Schlüsselwörter

heterocycles - benzophospholes - phospholes - phosphorus compounds - ring closure - aromatization

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