17.8.6 Chlorins (Dihydroporphyrins) (Update 2022)

Abstract

This is an update to the earlier Science of Synthesis contribution (Section 17.8.2.1) on chlorins, covering recent developments in reported methods for the synthesis and modifications of the chlorin core. The focus is mainly on the literature published in the period 2000–2021, and includes approaches for the synthesis of chlorins such as ring-closure reactions, oxidation or reduction of porphyrins, and cycloadditions.

Key words

chlorins - porphyrins - pyrroles - pyrrolidines - aldimines - aromaticity - alkynylation - acylation - formylation - natural products - total synthesis - asymmetric synthesis - cross-coupling reactions - pinacol rearrangement - ring-closure reactions

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