38.8.2.2 Medicinal Chemistry of Stable and Unstable 1,2-Dioxetanes: Origin, Formation, and Biological Activities

Abstract

This chapter describes the formation and transformation of stable and unstable 1,2-dioxetanes in various metabolic pathways. The chapter also describes the modern approaches to the synthesis of compounds with 1,2-dioxetane moiety, including molecules with chemiluminescence properties.

Schlüsselwörter

1,2-dioxetanes - peroxides - hydroperoxides - oxidation - singlet oxygen - cholesterol derivatives - vitamins - unsaturated compounds - oxidative cleavage - chemiluminescence

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