2.1 Reactions Involving an α,β-Unsaturated Carbonyl Compound or Analogue as Electrophilic Component
Book
Editor: Müller, T. J. J.
Title: Multicomponent Reactions, Volume 2
Subtitle: Reactions Involving an α,α-Unsaturated Carbonyl Compound as Electrophilic Component, Cycloadditions, and Boron-, Silicon-, Free-Radical-, and Metal-Mediated Reactions
Print ISBN: 9783131728319; Online ISBN: 9783132064317; Book DOI: 10.1055/b-003-125831
1st edition © 2014. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Subjects: Multicomponent Reactions
Science of Synthesis Reference Libraries
Parent publication
Title: Science of Synthesis
DOI: 10.1055/b-00000101
Series Editors: Carreira, E. M.; Decicco, C. P.; Fürstner, A.; Molander, G.; Schaumann, E.; Shibasaki, M.; Thomas, E. J.; Trost, B. M.
Type: Multivolume Edition
Abstract
This chapter focuses on multicomponent reactions involving an α, β-unsaturated compound as an electrophilic component and in which a Michael addition is a key step during the process. The Michael addition step can be either the starting point or a late event in the domino sequence. These reactions are extremely powerful processes, allowing the synthesis of diverse, valuable carbocyclic, heterocyclic, or acyclic scaffolds.
Key words
α, β-unsaturated compounds - Michael addition - domino reactions - carbocycles - heterocycles - stereoselective synthesis-
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