2.3.2 Organocatalyzed Addition to Activated C=C Bonds

P. Renzi; M. Moliterno; R. Salvio; M. Bella

Abstract

In this chapter, several examples of organocatalyzed additions to C=C bonds carried out through a domino approach are reviewed, from the early examples to recent applications of these strategies in industry.

Key words

organocatalysis - domino reactions - iminium ions - enamines - Michael/aldol reactions - nucleophilic/electrophilic addition - α,β-unsaturated carbonyl compounds - spirocyclic oxindoles - cinchona alkaloid derivatives - chiral secondary amines - Knoevenagel condensation - methyleneindolinones

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