5.4 Halogenation and Halocyclization of Alkenes

Abstract

Halogenated compounds are of high importance in many disciplines, even beyond chemistry. The unique properties that can be traced back to the halogen atom make the development of methods for selectively installing carbon—halogen bonds a rewarding goal. This chapter provides an overview of effective methods for the chemo-, regio-, and, in particular, stereoselective formation of C—X bonds using different oxidative approaches.

Key words

halogenation - halocyclization - dihalogenation - organocatalysis - hypervalent iodine - ion pairing - phosphoric acids - C3-symmetric trisimidazolines - amino ureas - Lewis base catalysis - hydrogen bonding - carbamates - thiocarbamates - dimeric cinchona alkaloids - Lewis acid catalysis - titanium - scandium

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