5.5 The Wacker Process

Abstract

The palladium-catalyzed Wacker process has been extended toward the oxidation of substituted α-alkenes and internal alkenes. Methods providing access to Markovnikov and anti-Markovnikov products in high selectivity are discussed.

Key words

Wacker oxidation - palladium catalysis - aldehyde-selective - ketone-selective - Markovnikov - anti-Markovnikov - oxidation - alkenes

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