9 Immobilized Reagents and Multistep Processes

Abstract

Multistep continuous-flow processing enables the direct preparation of complex chemical materials from simple input streams through a series of complexity-adding reaction steps. The use of polymer-supported reagents can greatly facilitate this process through the inline hosting of reagents or catalysts, the scavenging of spent materials or impurities, or even the temporary hosting of reactive intermediates prior to their reaction and release from the support. This chapter provides a comprehensive overview of such polymer-supported techniques.

Key words

polymer-supported reagents - multistep flow synthesis - natural products - pharmaceutical agents - catch and release

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