7 Borylative Ring Opening

M. Pineschi; C. Boldrini

Abstract

This review describes published methods for the direct introduction of a boron atom into organic molecules by ring opening of strained cyclic systems using nucleophilic diboron species. Considering the synthetic versatility of functionalized organoboron derivatives, the newly formed carbon–boron bond thus installed paves the way for a wide range of useful subsequent transformations.

Key words

borylation - nucleophilic diboron species - boronic esters - ring-opening reactions - vinyl epoxides - vinyl aziridines - vinylcyclopropanes - propargylic epoxides - propargylic aziridines - propargylic oxetanes - epoxides - aryl aziridines - transition-metal catalysis

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