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Fensterbank, L. et al.: 2021 Science of Synthesis, 2020/5: Free Radicals: Fundamentals and Applications in Organic Synthesis 2 DOI: 10.1055/sos-SD-233-00202
Free Radicals: Fundamentals and Applications in Organic Synthesis 2

2.12 Asymmetric Catalysis of Radical Reactions

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Editors: Fensterbank, L.; Ollivier, C.

Authors: Bartulovich, C. O.; Bolduc, T. G.; Chciuk, T. V.; Chemla, F.; Clark, K. F.; Cormier, M.; Das, A. ; Desage-El Murr, M. ; Dimitrova, D.; Fagnoni, M. ; Flowers, R. A.; Fukuyama, T. ; Goddard, J.-P. ; Hessin, C.; Liu, Z.-Q. ; Lu, Y.; Mitsudo, K.; Murphy, J. A.; Pérez-Luna, A. ; Protti, S. ; Qin, T. ; Ravelli, D. ; Ren, Y.; Ryu, I. ; Sammis, G. M.; Sibi, M. P.; Subramaniann, H.; Suga, S.; Sumino, S. ; Thomson, B.; Yamago, S.; Zhou, M.

Title: Free Radicals: Fundamentals and Applications in Organic Synthesis 2

Print ISBN: 9783132435544; Online ISBN: 9783132435551; Book DOI: 10.1055/b000000086

1st edition © 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

Science of Synthesis Reference Libraries



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.

Type: Multivolume Edition

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Abstract

Synthetic methodologies based on radical chemistry are efficient and powerful tools for the construction of carbon–carbon and carbon–heteroatom bonds. This chapter highlights the significance of asymmetric catalysis in free-radical reactions. Several asymmetric catalytic principles, ranging from early chiral Lewis acid and organocatalytic activation to recent photoredox and transition-metal-based asymmetric catalytic systems, are discussed.

Key words

asymmetric catalysis - radical reactions - chiral Lewis acids - hydrogen-atom transfer - chiral aluminum Lewis acids - chiral Brønsted acids - organocatalysis - photoredox catalysis - transition-metal catalysis - single-electron transfer - chiral porphyrins - chiral N-heterocyclic carbenes
 
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