12 Electrochemical C—C Bond Formation through Cross-Dehydrogenative Coupling

Abstract

Cross-dehydrogenative coupling is a challenging strategy that continues to evolve, as it avoids the typical requirements of prefunctionalization of substrates for C—C coupling transformations. Electrooxidation can be applied in dehydrogenative processes as a replacement for redox reagents, thereby making the protocol greener and more sustainable. In this review, recent developments in electrochemical dehydrogenative couplings for the construction of C—C bonds are summarized. There is a particular focus on the functionalization of C(sp²) and C(sp³) positions to access heterocyclic scaffolds, conjugated systems, and annulated frameworks.

Key words

cross-dehydrogenative coupling - electrochemical - electrosynthesis - C—C bond formation - sustainable processes - heterocycles - annulation

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