Mobile aortic arch thrombus: Conservative management with ticlopidine?

Philippe Dubois; Patrick Gurnet; Dariouch Dolatabadi; Guy Verhelst; Eric Vandueren; Eric Dubois; Guy Bruninx; Christian Delcour; Jean-Claude Wautrecht

doi:10.1007/BF01616423

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Int J Angiol 2001; 10(2): 149-152
DOI: 10.1007/BF01616423

Original Articles

Mobile aortic arch thrombus: Conservative management with ticlopidine?

Philippe Dubois¹ , Patrick Gurnet¹ , Dariouch Dolatabadi¹ , Guy Verhelst² , Eric Vandueren² , Eric Dubois² , Guy Bruninx² , Christian Delcour² , Jean-Claude Wautrecht³

¹Cardiology Department, CHU de Charleroi, Boulevard Paul Janson, Charleroi, Belgium
²Vascular Unit, CHU de Charleroi, Charleroi, Belgium
³Department of Vascular Diseases, Erasme University Hospital-Brussels, Free University of Brussels, Brussels, Belgium

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Publication History

Publication Date:
24 April 2011 (online)

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Abstract

Diffuse aortic atherosclerotic disease (AAD) is now well recognized as a potential source of cerebral and peripheral emboli. Its clinical importance has been demonstrated in patients over 60. We focus on an unusual presentation of AAD in younger patients free from significant diffuse aortic atherosclerosis, where the outstanding lesion was a large and highly mobile thrombus. Two cases of mobile aortic thrombi, which were conservatively managed with ticlopidine, a potent antiplatelet agent, are reported. Our two cases suggest a possible place of antiplatelet therapy with thienopyridine in the management of isolated large mobile aortic thrombus.