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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2015; 02(03): 121-125
DOI: 10.1007/s40556-015-0054-y
Review Article

Fetal Thrombotic Vasculopathy

Lily Marsden
1   Division of Pediatric Pathology, Department of Pathology, Primary Children’s Hospital, University of Utah, 100 N. Mario Capecchi Dr., 84113, Salt Lake City, UT, USA
,
Jessica Comstock
1   Division of Pediatric Pathology, Department of Pathology, Primary Children’s Hospital, University of Utah, 100 N. Mario Capecchi Dr., 84113, Salt Lake City, UT, USA
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Abstract

Fetal thrombotic vasculopathy (FTV) is the term used to encompass the histologic findings identified in placentas with fetal thrombotic lesions: occlusive and nonocclusive chorionic vessel thrombi, avascular villi in the distribution of a single villous tree, intramural vascular fibrin, and hemorrhagic endovasculitis. The underlying etiology of FTV is largely unknown though hypercoagulability and circulatory stasis have been the main focuses in the literature to explain the hemostatic abnormalities. This article reviews the literature in both defining and discussing, potential etiologies of FTV, as well as neonatal outcomes.

Keywords

Fetal thrombotic vasculopathy - Thrombophilia - Thrombosis - Avascular villi - Cerebral palsy


Publication History

Received: 02 July 2015

Accepted: 17 September 2015

Article published online:
08 May 2023

© 2015. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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