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DOI: 10.1007/s40556-016-0083-1
Cordocentesis
Abstract
Cordocentesis is an ultrasound-guided procedure to obtain fetal band from umbilical cord. It is indicated for rapid evaluation of fetal karyotype, fetal hematological disorders, and identification of fetal infection. Results are available in 48–72 h. If patient presents late and the results from amniocentesis would not be available within time for elective termination of pregnancy, it is the preferred procedure. Therapeutic indications include intravascular cord transfusion in Rh isoimmunization, fetal anemia, or drug administration. Procedure is performed from 18 weeks of gestation onward. Umbilical cord at placental attachment is the site of choice for puncture. We use 21–22 gauge spinal needle for this procedure. It needs expertise and is safe if performed by experienced surgeon. Single dose of antibiotic prior to procedure can be given. The rate of pregnancy loss varies and depends on the indication of procedure. Overall procedure related loss is <2 %.
Keywords
Cordocentesis - Prenatal diagnosis - Thalassemia - Hemophilia - Infection - Chromosomal diseasePublication History
Received: 13 October 2015
Accepted: 04 April 2016
Article published online:
08 May 2023
© 2016. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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