Screening for Preeclampsia

Abstract

Pre-eclampsia, still continues to be a major cause of maternal and fetal morbidity and mortality, inspite of being an active area of research. The importance of early prediction of pre-eclampsia lies in the fact that it allows for timely initiation of preventive therapy. A combination of biophysical and biochemical markers are superior to other tests for early prediction of the development of pre-eclampsia. With the inversion of pyramid of antenatal care, preeclampsia screening in the first trimester needs to become the standard of care. Researchers now talk of predicting preeclampsia even in the third trimester to increase surveillance.

Keywords

Pre-eclampsia - Early prediction - Maternal risk factors - Mean maternal arterial pressure - Ultrasound parameters - Biomarker - Pregnancy-associated plasma protein-A (PAPPA) - Placental growth factor

Publication History

Received: 16 October 2017

Accepted: 10 November 2017

Article published online:
08 May 2023